Clone: EP249
Host clonality: rabbit monoclonal
Control tissue: mammaglobin positive normal breast, breast carcinoma, skin
Staining pattern: cytoplasmic
Regulatory status: IVD, FDA Class I
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Product code:
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8240-C010: RTU, 10 capsules; 1 pack
8240-M250: RTU, 250 tests, 1 cartridge; 1 unit
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Low level of expression of mammaglobin is seen in normal breast. Its expression is markedly increased in breast carcinoma and is directly correlated with a higher grade. Mammaglobin is positive in about 80% of breast carcinomas, and is more frequently expressed than GCDFP-15.
Moderate to strong cytoplasmic reactivity for mammaglobin is seen in this invasive breast carcinoma.
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The epithelial cells of this invasive ductal carcinoma of breast, as well as the benign duct in the background, show predominantly weak to moderate membraneous reactivity for mammaglobin.
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Ducts and glomerular cells of the kidney show no reactivity for mammaglobin.