Clone: AE1/AE3/DC10
Host clonality: antibody cocktail
Control tissue: normal liver, esophagus, lung
Staining pattern: cytoplasmic
Regulatory status: IVD, FDA Class I
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Product code:
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8309-C010: 10 capsules, RTU; 1 pack
8309-M250: 1 cartridge, 250 tests, RTU; 1 unit
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Cytokeratins is a group of intermediate filament proteins expressed in cells of epithelial origin. The antibody cocktail of clones AE1, AE3, and DC10 labels both acidic and basic cytokeratins in normal and neoplastic cells.
![Tissue-Tek Genie<sup>®</sup><br /> anti-Cytokeratin Pan Antibody Cocktail [AE1/AE3/DC10]](/getattachment/57251b7d-fe5a-470f-aa2c-d4fe6b57b58d/File-Name "Tissue-Tek Genie<sup>®</sup><br /> anti-Cytokeratin Pan Antibody Cocktail [AE1/AE3/DC10]")
Intense cytoplasmic reactivity for PAN CK is seen in the epithelium of this prostate, while the background stroma is negative.
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Hepatocytes in this image show a moderate to strong cytoplasmic staining reaction with membranous accentuation.