Clone: OCH1E5
Host clonality: mouse monoclonal
Control tissue: liver, HCC
Staining pattern: granular cytoplasmic
Regulatory status: IVD, FDA Class I
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Product code:
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8374-C010: RTU, 10 capsules; 1 pack
8374-M250: RTU, 250 tests, 1 cartridge; 1 unit
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Hepatocyte Specific Antigen, also known as Hepatocyte Paraffin 1 (Hep Par 1), is expressed in normal and neoplastic hepatocytes. Hep Par 1 is a highly specific marker for HCC, although several non-hepatic tumors occasionally can show some Hep Par 1 positivity.
A diffuse strong granular cytoplasmic pattern is seen with Hep Par 1 staining in this HCC.
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This example of HCC shows a more variable staining reaction with Hep Par 1.
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Normal pancreatic tissues show a negative staining reaction with Hep Par 1.