Clone: RED2
Host clonality: rabbit monoclonal
Control tissue: normal colon, appendix, tonsil
Staining pattern: nuclear
Regulatory status: IVD, FDA Class I
Product code:
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8327-C010: RTU, 10 capsules; 1 pack
8327-M250: RTU, 1 cartridge, 250 tests; 1 unit
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MSH2 is expressed in normal proliferating cells and, when heterodimerized with MSH6 (MutS homolog 6), is involved in repairing DNA mutations which may occur during DNA replication.
Strong staining of normal appendix.
Strong staining of colon adenocarcinoma.
Negative staining of colon adenocarcinoma with loss of MSH2 expression.