Tissue-Tek Genie®
anti-CD138

Clone: B-A38
Host clonality: mouse monoclonal
Control tissue: tonsil, appendix, plasmacytoma, and CD138 positive DLBCL
Staining pattern: mainly membraneous and some cytoplasmic
Regulatory status: IVD, FDA Class I
Product code: 8241-C010: RTU, 10 capsules; 1 pack
8241-M250: RTU, 250 tests, 1 cartridge; 1 unit

 

CD138, also known as Syndecan-1, is a membrane protein which is involved in regulating cell morphology and adhesion. CD138 is predominantly expressed on mature plasma cells and early pre B-cells, in plasma cell malignancies, but not in mature mesenchymal and neural tissues. Various types
of epithelial cells are CD138 positive.
Tissue-Tek Genie<sup>&reg;</sup><br /> anti-CD138 Weak to moderate cytoplasmic staining for CD138 is demonstrated in the columnar epithelium of the appendix.

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Diffuse strong membrane staining is seen in this plasmacytoma.

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No expression of CD138 is seen in the neoplastic cells of this typical diffuse large B-cell lymphoma.
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